

"Automated multiplex protein screening from DNA to assay ready proteins in 48 hours"
Nuclera delivers the eProtein Discovery system, the first automated platform that screens, expresses, and purifies proteins in 48 hours. Using cell free synthesis on digital microfluidics, parallel screens identify optimal constructs, solubility tags, and expression conditions simultaneously. Scientists receive decision grade data on full length soluble proteins, eliminating wasted effort on poor candidates. Traditional protein production requires months of trial and error through cell culture. Nuclera tests hundreds of variables in 24 hours, then scales promising hits to microgram and milligram quantities. Researchers gain rapid access to challenging targets including membrane proteins and antibody fragments for structural studies.


135
Team Members
2013
Founded
Medical Devices
Sector
Hybrid
Work Environment
A world where every scientist has immediate access to high quality proteins, removing the trial and error bottleneck that delays breakthroughs in human health and accelerates discovery across structural biology and drug development.
Nuclera empowers every scientist to move from idea to assay ready proteins in days, not months, making protein access routine for every lab to accelerate breakthroughs in human health.