Location: Maidenhead
Work Mode: Remote
Requisition ID: 2678

About the Role
Alnylam is looking for an Associate Director of Clinical Pharmacology to join our team in Maidenhead. This is a leadership position responsible for the design, execution, and interpretation of clinical pharmacology studies and the development of clinical pharmacology strategies for RNAi therapeutic programs.

Key Responsibilities

• Lead the development and implementation of clinical pharmacology strategies for assigned drug development programs.
• Design, oversee, and interpret clinical pharmacology studies, including PK/PD, drug-drug interaction, and special population studies.
• Collaborate with cross-functional teams including Clinical Development, Regulatory Affairs, and Biostatistics to ensure integrated development plans.
• Represent Clinical Pharmacology in interactions with global regulatory agencies.
• Provide expert scientific input into clinical study protocols, investigator brochures, and regulatory submission documents (e.g., IND, NDA, MAA).
• Stay current with emerging trends and regulatory requirements in clinical pharmacology and RNAi therapeutics.

Requirements

• PhD, PharmD, or MD in Clinical Pharmacology, Pharmacokinetics, or a related field.
• Significant experience in clinical pharmacology within the pharmaceutical or biotech industry.
• Strong understanding of PK/PD modeling and simulation principles.
• Proven track record of leading clinical pharmacology components of successful regulatory submissions.
• Excellent communication and leadership skills with the ability to influence cross-functional teams.

Alnylam is an equal opportunity employer and values diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.