The Role:
Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology, with a diverse pipeline of development programs across various diseases. As an employee, you'll be part of a continually growing organization, working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives. Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience, with the potential to make a significant impact on patients' lives worldwide.

Moderna's mission is to establish a leading-edge research, development, and manufacturing facility at Harwell, as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic, NHS and government partners across the UK. We're looking for global experts eager to join us in this endeavour, contributing to a future where access to life-saving vaccines is a reality for all.

We are seeking a hands-on and technically adept GxP IT Systems Engineer to support Moderna’s manufacturing operations at our Harwell site. This is a highly interactive role embedded in site operations, working alongside automation engineers, QC analysts, warehouse teams, and manufacturing operators. You will serve as the critical link between IT and Operational Technology (OT), delivering robust, compliant systems performance and exceptional end-user support.

This is a dynamic opportunity for an individual contributor who thrives in complex, regulated environments and enjoys maintaining the technical backbone that drives GMP production. With exposure to modern observability, cybersecurity tooling, and the potential to work closely with Generative AI and automation systems, this position places you at the forefront of digital manufacturing in biotechnology.

Here’s What You’ll Do:
Your key responsibilities will be:

• Ensure compliance with GMP and data integrity standards, supporting inspections, audits, deviations, CAPAs, and SOP adherence.
• Provide Tier 1 support for manufacturing operations, responding to shop floor issues across workstations, HMIs, scanners, label printers, and Thin Clients.
• Triage and resolve IT incidents, requests, and change controls using a service-oriented mindset and SLAs.
• Manage infrastructure operations including troubleshooting of Windows servers, VMs (VMware/Hyper-V), Active Directory, DNS/DHCP, and time sync services.
• Support change execution activities in a validated GxP environment, maintaining audit trails and system states.
• Use observability tools such as Dynatrace, Splunk, and PagerDuty to monitor system health and resolve performance issues.
• Participate in endpoint protection and vulnerability management in coordination with security teams using tools like CrowdStrike.
• Maintain CMDB accuracy, system inventories, configuration baselines, and network documentation.

Your responsibilities will also include:

• Provide day-to-day end-user IT support, including configuration and maintenance of laptops, mobile devices, and peripherals.
• Diagnose and resolve issues related to OS, Microsoft Office Suite, Outlook, and third-party applications.
• Maintain detailed documentation for tickets, repairs, imaging, data wiping, and asset tracking.
• Deliver a high-quality, customer-centric experience in all end-user interactions.
• Collaborate with QA, QC, Automation, Plant and Lab Engineering, and Digital Core teams to coordinate system downtime, restoration, and change advisory reviews.
• Participate in after-hours or weekend support activities as needed based on manufacturing demands.

Here’s What You’ll Bring to the Table:
Education and Experience

• Bachelor's degree in computer science, Information Technology, Industrial Engineering, physical science or related field or relevant experience.
• Minimum of 3-5 years of experience supporting IT/OT systems in manufacturing and labs.
• Experience working in a BioPharma, GxP environment
• Some experience working with virtual environment (VMware/Hyper-V) and/or cloud platform (AWS preferred)
• Some experience working with RDBMS (SQL Server or Oracle)
• Some experience working with backup/recovery systems (Acronis, Veeam, N2WS, etc.)
• Some experience working with Cybersecurity endpoint protection applications (CrowdStrike, Symantec, McAfee, Carbon Black, etc.)
• Some experience working with infrastructure tools (Dynatrace, Pager Duty, Splunk)
• Excellent Windows and Microsoft Office Suite trouble shooting skills, as well as hardware trouble shooting skills.
• Experience with Apple device support for both MacOS and iOS, including the JAMF environment
• Experience with Service Now a plus
• Basic understanding of network routing, switching and firewall concepts.

Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That’s why our global benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Best-in-class healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being with access to fitness, mindfulness, and mental health support
• Family building benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

Moderna is committed to equal opportunity in employment and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.