Make your mark for patients

To strengthen our Non-Clinical Safety Evaluation group within Early Clinical Development and Translational Science, we are looking for a talented individual for the role of Non-Clinical Safety Lead, based in Slough, UK.

About the role
As a Non-clinical Safety Lead, you will provide scientific leadership for non-clinical safety across discovery and development programs. You will shape non-clinical strategies, ensure high-quality execution, and support regulatory interactions from early development through clinical progression and post approval.

Key Responsibilities

• Lead, communicate, and execute non-clinical safety strategies aligned with clinical development goals.
• Develop integrated non-clinical safety plans supporting innovative programs. Ensure timely delivery of high-quality non-clinical data and global regulatory documentation.
• Represent UCB in interactions with regulatory authorities and external partners.
• Provide non-clinical safety expertise to discovery and development projects.
• Partner with clinical teams to ensure robust preclinical data supports clinical trial design.
• Contribute to global regulatory submissions (e.g., IBs, Briefing Books, INDs, NDA/BLAs) and interact with regulatory authorities.
• Oversee the design, review, and interpretation of non-clinical studies.
• Manage non-clinical safety programs, including budgets.

Education, Experience and Skills

• PhD in Toxicology, Pharmacology, or related discipline (or equivalent MS/DVM with experience).
• 5+ years in non-clinical safety (preferably in pharma or biotech).
• Deep understanding of regulatory processes and regulatory toxicology.
• Experience managing and forecasting non-clinical safety budgets.
• Ability to produce high-quality reports and submission documents with subject matter expert support.

Preferred Qualifications

• Accredited or registered toxicologist.
• Experience in gene and cell therapy and/or other novel modalities.

About UCB
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9,000 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We’ve embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.