
Simbec-Orion
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"A specialist clinical research organisation advancing medicines from early to late phase trials"
About Simbec-Orion
Simbec-Orion delivers clinical trial management from first-in-human studies through Phase III and post-marketing work. It specialises in clinical pharmacology, oncology and rare diseases, supporting small and mid-sized biotechnology and pharmaceutical companies. Services include clinical operations, biometrics, central laboratory testing, pharmacovigilance and regulatory support.
Headquartered in Merthyr Tydfil, the company has offices in Europe, North America and Asia-Pacific. Its South Wales clinical pharmacology facility includes an MHRA-accredited Phase I unit with 48 beds and on-site laboratories. Simbec-Orion joined Caidya in June 2026, bringing its early-phase and specialist trial capabilities into the combined clinical research business.

Teams across clinical development
Clinical research and scientific advisory specialists work alongside laboratory and biometrics teams. The company describes a centralised leadership structure and teams that adapt their communication and delivery to each client’s study, connecting scientific input with trial operations and reporting.
Feedback across disciplines
An annual client satisfaction survey informs project improvements and a Rewards and Recognition programme. Client nominations have included colleagues in project management, clinical operations, regulatory affairs, technical writing, statistics, data management and laboratory services, reflecting the breadth of work involved in delivering studies.

350
Team Members
1976
Founded
Contract Research
Sector
Hybrid
Work Environment
Open Positions
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