Research Lead (Formulation Sciences)
Location: London
Hybrid working: 3 days a week in the office (currently Tuesday, Wednesday, and one other day depending on team)

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

Your impact
As part of the ongoing expansion of our Drug Design and Medical Research function (DDMR), we are looking to recruit a Formulation expert keen to impact drug discovery projects.

You will support the business alongside world leading AI/ML Drug Design Platform teams, collaborating to deliver scientific expertise and strategic direction to drive improvements in the Platform and apply this to real drug design projects.

As a member of the DPC and Preclinical formulation team, you will be responsible for supporting the rapid progression of multiple drug discovery/DPC and preclinical development projects by providing (pre)-formulation expertise to program teams, leveraging significant external CRO resources.

What you will do

• Develop and execute comprehensive (pre)-formulation strategies for small molecules across the drug discovery and preclinical development lifecycle, working closely with the drug design, preclinical and CMC functions.
• Design and refine innovative formulation technologies, such as solid dispersions and co-crystals, to optimise solubility, stability, and manufacturability.
• Develop and interpret stability studies utilising ICH and ASAP methodologies, while implementing rigorous in-process controls to ensure product performance.
• Collaborate across multi-disciplinary preclinical teams to deliver seamless and integrated solutions.
• Author technical reports, protocols, and regulatory submissions in strict alignment with internal policies and global regulatory requirements.

Essential skills and qualifications

• PhD in pharmaceutical science, or a related technical field, or equivalent experience.
• 6+ years of professional experience within a biotech or pharma setting.
• Demonstrated expertise in the development of oral solid dosage forms.
• Demonstrated experience of supporting IND packages.
• Deep technical proficiency in preformulation, manufacturing processes, and the implementation of advanced drug delivery technologies.
• Rigorous understanding of global regulatory guidelines, including ICH and FDA.
• Excellent communication (written and verbal), interpersonal and influencing skills, with an ability to work effectively in a cross-functional, collaborative team environment.

Nice to have

• Specialised knowledge and practical experience in the development of amorphous dispersions.

Creating an extraordinary company
We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please let us know.

Apply via the company portal.