Job Description

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science", great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

We have an exciting opportunity for a new Associate Principal Scientist to join our Oncology health economic modeling team in the Health Economic and Decision Sciences group. The preferred location for this role is West Point, PA; although alternate locations may be considered, including Rahway, NJ; Boston, MA; the UK, and Switzerland. Hybrid and flexible work arrangements are possible, consistent with local office and country policies.

The Health Economic and Decision Sciences (HEDS) department is part of our Company's Biostatistics and Research Decision Sciences (BARDS) organization. BARDS is responsible for strategic design and analysis to enable informed decision making in the discovery, development and delivery of our Company's innovative products, and is a leader in quantitative scientific methodology and its application to enable the targeting, discovery, development, manufacturing, and marketing of drugs and vaccines for the benefit of patients and global public health. In collaboration with internal and external partners, the BARDS-HEDS department specifically provides strategic and technical leadership to enable patient access, measure and quantify the value of our Company's products, inform internal and external decisions, and shape methodology and external health policy and practice. This position will focus on health economic modeling for oncology products.

Role
Under the direction of an HEDS Senior Director, the Associate Principal Scientist provides strategic development and use of industry-leading predictive and economic models to enhance our understanding of disease and to quantify and communicate the value of our oncology products to patients, providers, and payers.

• Serve as the BARDS HEDS lead for one or more Value and Implementation teams to develop health economic, disease, and predictive models to enable business insights for the product.
• Utilize discovery, real world evidence, clinical trial and published data, and publicly available information and tools to provide economic and integrated models to answer key questions in all phases of drug and vaccine development - Phase I through loss of data exclusivity.
• Advance the use of integrated quantitative approaches, focusing on economic, disease, and predictive modeling and simulation in partnership with other internal groups and external organizations.
• Development and maintenance of health quality global health economic models and tools in-house or in collaboration with external vendors to provide critical business insights and fully demonstrate the value of our company's products.
• Support and training of HEDS models and tools to support country/regional team adaptations and communications with external stakeholders.
• Dissemination of health economic data via presentations at congresses and publications in scientific journals.
• Work closely with external collaborators (clinical/economic thought leaders, payer/HTA experts, alliance partners) and internal cross-functional teams to ensure that new methodologies, models and advanced analytics are fully utilized for our products.
• Maintain awareness of external data, modeling methodologies and IT tools to collaborate across relevant internal stakeholders to enhance our Company's capabilities in health economic modeling, simulation, and data visualization.
• Ensure sharing of work product and relevant best practices across our Company's enterprise.

Education
PhD (preferred) or Master's degree, in Health Economics, Biostatistics, Health Services Research, Actuarial Sciences, Operations Research or a closely related quantitative field

Required Experience and Skills:

• Relevant work experience in health economics and outcomes research (HEOR) beyond PhD or Master's degree
• Knowledge and experience in economic evaluation of oncology drugs and interventions
• Expertise and solid hands-on experience in the conceptualization, design, development and dissemination of health economic model approaches to enable internal and external decisions
• Track record of submissions to Health Technology Assessment bodies and research publications in conferences and peer-reviewed journals
• Strong interpersonal, organizational and communication skills with ability to interact with individuals from a variety of disciplines
• Understanding of the market access environment and challenges in the US and key international markets

#eligibleforERP

Required Skills:
Data Management, Economic Modeling, Health Economics, Health Economics Evaluation, Health Technology Assessment (HTA), Oncology, Researching, Stakeholder Relationship Management, Strategic Planning

Employee Status: Regular
Relocation: Domestic
VISA Sponsorship: Yes
Travel Requirements: 10%
Flexible Work Arrangements: Hybrid
Shift: Not Indicated
Valid Driving License: No
Hazardous Material(s): n/a
Job Posting End Date: 10/26/2026

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.