Job summary
Applications are invited from experienced State Registered Clinical Scientists in Rare Disease Genomics with DipRCPath or FRCPath.

You will be joining the team at the North Thames Rare Disease Genomics Laboratory at Great Ormond Street Hospital. We are seeking enthusiastic, self-motivated Scientists with experience of clinical genomics service delivery and a sound understanding of genomic techniques including variant assessment. Accomplished communication and organisational skills are required. An interest in Quality Management, Training or Laboratory Health and Safety would be advantageous. You will lead a team within our core, specialist or prenatal genomics service. Our scientific teams are cross-discipline with opportunities for cytogenetics and molecular genetics across the department. Applications are welcome from scientists with cytogenetics or molecular genetics experience, although a positive attitude to genomic analysis of all types is required. We support trained scientists who wish to adopt flexible and/or partially remote working patterns.

Main duties of the job
The GOSH Genomics Laboratory has an establishment of approximately 180 including Technologists, Clinical Scientists, Translational Scientists, Bioinformaticians and Administrative Support staff. Along with two Clinical Genetics Teams we form a strategic Genetics Unit within the hospital and provide North London with a Regional Genetics Service serving a population of approximately 10 million. The laboratory provides an in-house diagnostic service for paediatric and inherited cancer, molecular and cytogenetic testing in accordance with the NHS England Genomic Test Directory. This includes services for 11 of the designated specialist areas for the NHSE Genomic Medicine Service. Genomic testing is provided for both prenatal and postnatal samples using SNP microarray, karyotyping, FISH, qPCR, MLPA, Next generation sequencing, rapid genome sequencing, and various targeted tests. We are also engaged in the delivery of the NHSE GMS Whole Genome Sequencing programme for our North Thames patients.We are involved in a number of collaborative research and development projects with colleagues at the UCL Institute of Child Health and Institute of Neurology as part of the UCL Partners Academic Health Sciences Centre. We host a team of Translational and Research Scientists focusing on translation of new genomic technologies to the diagnostic service.

About us
GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.

We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.

We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.

We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.

We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women's staff networks. Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.

Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below.

Person Specification
GOSH Culture and Values
Essential

• Our Always values

Academic/Professional qualification/Training
Essential

• 1st or 2nd class honours degree in a relevant biological subject
• State Registered Clinical Scientist (HCPC)
• Commitment to RCPath Fellowship
• RCPath Part 1

Desirable

• Higher degree or externally assessed equivalent level of knowledge and expertise within the speciality of Genetics/Genomics
• Royal College of Pathologists Fellowship (FRCPath)

Experience/Knowledge
Essential

• Post-registration experience in a regional clinical genomics rare and inherited disease service
• Extensive and comprehensive knowledge of genomic diagnostic methods required in a regional clinical genomics rare and inherited disease service
• Up to date knowledge of scientific literature and best practice guidance relating to molecular genetic and cytogenetic tests
• Knowledge of appropriate Quality Management and Audit regulations and requirements
• Evidence of an active programme of continuing professional development

Desirable

• To have completed a formal postgraduate training programme approved as appropriate for registration together with in service experience
• Experience of molecular cytogenetics techniques and their application within a regional clinical cytogenetics service
• Experience of participation in external quality assessment schemes for genomic tests
• Experience of training pre-registration scientists
• Knowledge of appropriate Health and Safety regulations and requirements

Skills/Abilities
Essential

• Positive, "can do" attitude to work
• Evidence of good inter-personal communication skills
• Skilled in the microscopic diagnosis of chromosome abnormality
• Skilled in the interpretation and reporting of complex genomic results, including giving advice on the implications and reproductive risks for patients and families
• Able to critically analyse and interpret scientific data
• Verbal and written presentation and communication skills. Able to present data at departmental and inter-departmental meetings.
• Ability to write and authorize normal, abnormal and complex reports
• Computer literate including use of Genetic databases and analytical software

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).