Job summary
University Hospital Southampton NHS Foundation Trust is delighted to offer a fantastic opportunity to work with us.

Please see below for detailed job description of the role.

Main duties of the job
We have an exciting opportunity for an experienced research nurse who also has clinical experience of Critical Care to join our Critical Care Research Team.

The Critical Care Research Sister plays a pivotal role in delivering high-quality clinical research within a busy and dynamic critical care environment.

The post holder will support the development, coordination and delivery of a portfolio of commercial and non-commercial research studies, ensuring that patients and their families have the opportunity to participate in research that advances patient care and improves clinical outcomes.

The successful candidate will work closely with multidisciplinary teams including consultants, nurses, allied health professionals, research practitioners, and external sponsors to identify, recruit and support study participants, whilst ensuring studies are conducted in accordance with Good Clinical Practice (GCP), Trust policies and regulatory requirements.

This role contributes directly to UHS's commitment to providing world-class patient care, advancing evidence-based practice and maintaining its reputation as a leading research-active teaching hospital. The post holder will report to the Senior Research Sister and work collaboratively within the wider Trust Wide Research Team.

About us
As one of the largest acute teaching Trusts in England, we offer learning and development opportunities to help you achieve the career you aspire to. UHS is rated 'Good' by the CQC and in the latest national NHS Staff Survey, we were in the top 10 acute trusts for staff engagement and for staff recommending the hospital as a place to work or receive care.

We support flexible working and will consider requests taking into account the needs of the service. UHS employees are able to access a range of NHS discounts, are entitled to a minimum of 35 days paid holiday (pro rata), and we offer a generous pension scheme.

Southampton is an attractive place to live and work situated on the south coast, with an international airport and direct trains to London. The New Forest National Park and beaches of the Jurassic coast are also right on our doorstep. The city offers living costs 30% lower than London and 17 schools rated outstanding by Ofsted.

We believe that using technology wisely shows strong time management and commitment to innovation. However, personalising your recruitment application to highlight your unique skills and experiences is crucial. Relying too heavily on generic, AI-generated content instead of drawing from your own strengths and accomplishments may lead to your application being rejected if multiple candidates present identical or similar information.

Details
Date posted: 11 August 2026
Pay scheme: Agenda for change
Band: Band 6
Salary: Depending on experience
£39,959 to £48,117 per annum, pro rata
Contract: Permanent
Working pattern: Full-time, Part-time
Reference number: 188-THQ060826
Job locations: RD Trustwide Research Nurses, Tremona Road, Southampton, SO16 6YD, United Kingdom

Job responsibilities
Responsibilities Coordinate and deliver a portfolio of clinical research studies within Critical Care, ensuring compliance with study protocols, GCP standards and regulatory requirements. Identify, screen, recruit and support patients and relatives participating in research studies, obtaining informed consent or consultee agreement where appropriate. Collect, document and maintain accurate research data and study records to ensure data quality, audit readiness and participant safety. Work collaboratively with multidisciplinary teams, sponsors and research networks to support successful study delivery and achievement of recruitment targets.

Experience/Skills required Registered Nurse (Adult) with current NMC registration. Clinical experience within Critical Care. Experience of delivering or supporting clinical research studies, including knowledge of research governance and Good Clinical Practice (GCP). Excellent communication and interpersonal skills, with the ability to engage effectively with patients, relatives and multidisciplinary teams. Strong organisational skills with the ability to manage multiple studies, prioritise workload and work independently within a fast-paced environment.

Additional Requirements Willingness and ability to work flexibly to meet study requirements, including working early, late or weekend working where required. Ability to travel between Trust sites and external meetings as required. Successful candidates will be required to undergo the appropriate NHS employment checks, including an enhanced DBS check. Evidence of ongoing professional development and commitment to maintaining clinical and research competencies.

For an overview of the position, please refer to the attached Job Description and Person Specification document. This includes a detailed breakdown of the key responsibilities, role expectations, and the qualifications we are looking for.

Person Specification
Qualifications, knowledge and experience
Essential

• Registered Nurse / Statutory Registered Allied Health Professional on relevant part of the register NMC / HCPC
• Evidence of on-going professional development
• Post registration experience in a relevant clinical speciality
• Recent NHS experience or equivalent
• Provide evidence of teaching and supporting learners in practice

Desirable

• International Conference on Harmonisation/Good Clinical Practice (ICH/GCP) Certification
• Venesection and cannulation
• Clinical Research experience
• Ward/department management experience
• Knowledge of UK Policy Framework for Health & Social Care, ICH/GCP
• Experience as an NMC sign-off mentor or clinical practice assessor

Trust Values and Behaviours
Essential

• Patients First
• Always Improving
• Working Together

Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration
Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details
Employer name: University Hospital Southampton NHS Trust
Address: RD Trustwide Research Nurses, Tremona Road, Southampton, SO16 6YD, United Kingdom
Employer's website: https://www.uhs.nhs.uk/home.aspx (Opens in a new tab)

Employer contact details
For questions about the job, contact:
Research Sister
Susan Jackson
susan.jackson@uhs.nhs.uk
02381205308

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications.
Applicants must have current UK professional registration.